* Impurities refer to the presence of complexing proteins, inactive neurotoxin, flagellin and bacterial DNA contaminants.1 / + Pure refers to the absence of complexing proteins, inactive neurotoxin, flagellin and bacterial DNA contaminants.1 It also contains immunologically inert excipients.2,3 / ^ 與其他香港註冊肉毒桿菌素品牌比較1,2 ; 香港註冊藥劑製品: www.drugoffice.gov.hk/ # No.1 Imported brand in Korea. Based on MFDS's 2020 Total Imports (50U + 100U) Record Data / 1. Park JY, et al. Neurotoxin impurities: A Review of Threats to Efficacy. Plast Reconstr Sur Glob Open.2020;8(1):e2627 / 2. Martin, M.U.; Frevert, J.; Tay,C.M. Complexing Protein-Free Botulinum Neurotoxin A Formulations: Implications of Excipients for Immunogenicity. Toxins 2024, 16, 101. / 3. Martin MU, Frevert J, Park J-Y, Cui H, Curry A, Loh WQ. Immunological Considerations of Polysorbate as an Excipient in Botulinum Neurotoxin Type A Formulations: A Narrative Review. Toxins. 2025;17(12):598 / 4. Imhof M, Kühne U. A Phase ilI Study of IncobotulinumtoxinA in the Treatment of Glabellar Frown Lines. 2011; 4(10):28-34 / 5. Prager W, et al. Clin Interv Aging. 2013;8:449-56 6. Rappi T, et al. Clin Cosmet Investig Dermatol. 2013; Sep 24: 6:211-19 / 7. Kane MA, et al. Dermatol Surg. 2015;41(11):1319. / 8. Sattler G, et al. Dermatol Surg 2010;36(Suppl 4):2146–54 / 9. Prager W, et al. Dermatol Surg 2010; 36(Suppl 4):2155–60. / 10. Fischer T, et al. J Drugs Dermatol. 2020;19(5):461-469. / 11. Chao YY, et al. J Clin Aesthet Dermatol. 2019;12(12):E53-E57 / 12. Saybel A, et al. J Drugs Dermatol 2015;14(11):1291- 1296. / 13. XEOMIN® Approved Product Information. Aug 2021. / 14. 資料來源:根據2024年一項由Merz Aesthetics聯同Frost & Sullivan 於9個亞太地區進行關於「肉毒桿菌素抗藥性」的消費者研究調查,合共2,588名使用肉毒桿菌素的受訪對象 (曾注射三次或以上含雜質的肉毒桿菌素),年齡介乎21至55歲。